1: Ong Q*, Wee W, Dela Cruz J, Teo JWR, Han W.* 222-Nanometer Far-UVC Exposure Results in DNA Damage and Transcriptional Changes to Mammalian Cells. Int J Mol Sci. 2022 Aug 14;23(16):9112. doi: 10.3390/ijms23169112. PMID: 36012379; PMCID: PMC9408858.

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2: Tan SLW, Israeli E, Ericksen RE, Chow PKH, Han W*. The altered lipidome of
hepatocellular carcinoma. Semin Cancer Biol. 2022 Feb 4:S1044-579X(22)00025-6.
doi: 10.1016/j.semcancer.2022.02.004. Epub ahead of print. PMID: 35131480.

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3: So WY, Liu WN, Teo AKK, Rutter GA, Han W*. Paired box 6 programs essential
exocytotic genes in the regulation of glucose-stimulated insulin secretion and
glucose homeostasis. Sci Transl Med. 2021 Jun 30;13(600):eabb1038. doi:
10.1126/scitranslmed.abb1038. PMID: 34193609.

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4: Tan HYA, Sim MFM, Tan SX, Ng Y, Gan SY, Li H, Neo SP, Gunaratne J, Xu F, Han
W.* HOXC10 Suppresses Browning to Maintain White Adipocyte Identity. Diabetes.
2021 Aug;70(8):1654-1663. doi: 10.2337/db21-0114. Epub 2021 May 14. PMID:
33990396; PMCID: PMC8385616.

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5: Shrestha MM, Lim CY, Bi X, Robinson RC, Han W.* Tmod3 Phosphorylation Mediates AMPK-Dependent GLUT4 Plasma Membrane Insertion in Myoblasts. Front Endocrinol (Lausanne). 2021 Apr 20;12:653557. doi: 10.3389/fendo.2021.653557. PMID:33959097; PMCID: PMC8095187.

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6: Ding Z, Ericksen RE, Lee QY, Han W.* Reprogramming of mitochondrial proline
metabolism promotes liver tumorigenesis. Amino Acids. 2021 Dec;53(12):1807-1815.
doi: 10.1007/s00726-021-02961-5. Epub 2021 Feb 28. PMID: 33646427.

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7: Chong YC, Toh TB, Chan Z, Lin QXX, Thng DKH, Hooi L, Ding Z, Shuen T, Toh
HC, Dan YY, Bonney GK, Zhou L, Chow P, Wang Y, Benoukraf T, Chow EK, Han W.*
Targeted Inhibition of Purine Metabolism Is Effective in Suppressing
Hepatocellular Carcinoma Progression. Hepatol Commun. 2020 Jul
27;4(9):1362-1381. doi: 10.1002/hep4.1559. PMID: 32923839; PMCID: PMC7471427.

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8: Ericksen RE, Han W.* Give and take: competition for BCAAs in the tumour
microenvironment. Nat Metab. 2020 Aug;2(8):657-658. doi:10.1038/s42255-020-0239-0. PMID: 32694826.

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9: Han W, Eizirik DL. The pancreatic beta cells: Still much to be learned.
Semin Cell Dev Biol. 2020 Jul;103:1-2. doi: 10.1016/j.semcdb.2020.04.020. Epub
2020 May 13. PMID: 32417218.

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10: Bai B, Yang W, Fu Y, Foon HL, Tay WT, Yang K, Luo C, Gunaratne J, Lee P,
Zile MR, Xu A, Chin CWL, Lam CSP, Han W*, Wang Y*. Seipin Knockout Mice Develop Heart Failure With Preserved Ejection Fraction. JACC Basic Transl Sci. 2019 Nov 20;4(8):924-937. doi: 10.1016/j.jacbts.2019.07.008. PMID: 31909301; PMCID:
PMC6939002.

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11: Ding Z, Ericksen RE, Escande-Beillard N, Lee QY, Loh A, Denil S, Steckel M,
Haegebarth A, Wai Ho TS, Chow P, Toh HC, Reversade B, Gruenewald S, Han W*.
Metabolic pathway analyses identify proline biosynthesis pathway as a promoter
of liver tumorigenesis. J Hepatol. 2020 Apr;72(4):725-735. doi:
10.1016/j.jhep.2019.10.026. Epub 2019 Nov 11. PMID: 31726117.

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12: Ericksen RE, Han W* Malignant manipulaTORs of metabolism: suppressing BCAA
catabolism to enhance mTORC1 activity. Mol Cell Oncol. 2019 Mar 20;6(3):1585171.
doi: 10.1080/23723556.2019.1585171. PMID: 31131306; PMCID: PMC6512911.

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13: Ericksen RE, Lim SL, McDonnell E, Shuen WH, Vadiveloo M, White PJ, Ding Z,
Kwok R, Lee P, Radda GK, Toh HC, Hirschey MD, Han W*. Loss of BCAA Catabolism
during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression. Cell Metab. 2019 May 7;29(5):1151-1165.e6. doi:
10.1016/j.cmet.2018.12.020. Epub 2019 Jan 17. PMID: 30661928; PMCID: PMC6506390.

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14: Chong YC, Lim TE, Fu Y, Shin EM, Tergaonkar V, Han W*. Indian Hedgehog links
obesity to development of hepatocellular carcinoma. Oncogene. 2019
Mar;38(12):2206-2222. doi: 10.1038/s41388-018-0585-5. Epub 2018 Nov 23. PMID:
30470823.

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15: Ong Q, Han W, Yang X. O-GlcNAc as an Integrator of Signaling Pathways. Front
Endocrinol (Lausanne). 2018 Oct 16;9:599. doi: 10.3389/fendo.2018.00599. PMID:
30464755; PMCID: PMC6234912.

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16: Luo SX, Huang J, Li Q, Mohammad H, Lee CY, Krishna K, Kok AM, Tan YL, Lim
JY, Li H, Yeow LY, Sun J, He M, Grandjean J, Sajikumar S, Han W, Fu Y.
Regulation of feeding by somatostatin neurons in the tuberal nucleus. Science.
2018 Jul 6;361(6397):76-81. doi: 10.1126/science.aar4983. PMID: 29976824.

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17: Peng X, Zhang Q, Liao C, Han W, Xu F. Epigenomic Control of Thermogenic
Adipocyte Differentiation and Function. Int J Mol Sci. 2018 Jun 17;19(6):1793.
doi: 10.3390/ijms19061793. PMID: 29914202; PMCID: PMC6032041.

 

18: Ng R, Hussain NA, Zhang Q, Chang C, Li H, Fu Y, Cao L, Han W, Stunkel W, Xu
F. miRNA-32 Drives Brown Fat Thermogenesis and Trans-activates Subcutaneous
White Fat Browning in Mice. Cell Rep. 2017 May 9;19(6):1229-1246. doi:
10.1016/j.celrep.2017.04.035. PMID: 28494871; PMCID: PMC5637386.

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19: Sim CK, Kim SY, Brunmeir R, Zhang Q, Li H, Dharmasegaran D, Leong C, Lim YY,
Han W, Xu F. Regulation of white and brown adipocyte differentiation by RhoGAP
DLC1. PLoS One. 2017 Mar 30;12(3):e0174761. doi: 10.1371/journal.pone.0174761.
PMID: 28358928; PMCID: PMC5373604.

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20: Julien SG, Kim SY, Brunmeir R, Sinnakannu JR, Ge X, Li H, Ma W, Yaligar J,
Kn BP, Velan SS, Röder PV, Zhang Q, Sim CK, Wu J, Garcia-Miralles M, Pouladi MA,
Xie W, McFarlane C, Han W, Xu F. Narciclasine attenuates diet-induced obesity by
promoting oxidative metabolism in skeletal muscle. PLoS Biol. 2017 Feb
16;15(2):e1002597. doi: 10.1371/journal.pbio.1002597. PMID: 28207742; PMCID:
PMC5331945.

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21: Ng Y, Tan SX, Chia SY, Tan HY, Gun SY, Sun L, Hong W, Han W*. HOXC10
suppresses browning of white adipose tissues. Exp Mol Med. 2017 Feb
10;49(2):e292. doi: 10.1038/emm.2016.144. PMID: 28186086; PMCID: PMC5336557.

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22: Liu T, Li H, Hong W, Han W.* Brefeldin A-inhibited guanine nucleotide
exchange protein 3 is localized in lysosomes and regulates GABA signaling in
hippocampal neurons. J Neurochem. 2016 Dec;139(5):748-756. doi:
10.1111/jnc.13859. Epub 2016 Oct 27. PMID: 27696409.

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23: Chen N, Sugihara H, Kim J, Fu Z, Barak B, Sur M, Feng G, Han W*. Direct
modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally
regulates feeding. Elife. 2016 Oct 18;5:e18716. doi: 10.7554/eLife.18716. PMID:
27751234; PMCID: PMC5068968.

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24: Röder PV, Wong X, Hong W, Han W*. Molecular regulation of insulin granule
biogenesis and exocytosis. Biochem J. 2016 Sep 15;473(18):2737-56. doi:
10.1042/BCJ20160291. PMID: 27621482.

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25: Li H, Kek HC, Lim J, Gelling RW, Han W. Green tea
(-)-epigallocatechin-3-gallate counteracts daytime overeating induced by high-
fat diet in mice. Mol Nutr Food Res. 2016 Dec;60(12):2565-2575. doi:
10.1002/mnfr.201600162. Epub 2016 Sep 1. PMID: 27468160.

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26: Wu B, Wei S, Petersen N, Ali Y, Wang X, Bacaj T, Rorsman P, Hong W, Südhof
TC, Han W*. Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells. Proc Natl Acad Sci U S A. 2015 Aug
11;112(32):9996-10001. doi: 10.1073/pnas.1513004112. Epub 2015 Jul 27. PMID:
26216970; PMCID: PMC4538675.

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27: Lim CY, Bi X, Wu D, Kim JB, Gunning PW, Hong W, Han W*. Tropomodulin3 is a
novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through
cortical actin remodeling. Nat Commun. 2015 Jan 9;6:5951. doi:
10.1038/ncomms6951. PMID: 25575350; PMCID: PMC4354152.

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28: Ma W, Fuentes G, Shi X, Verma C, Radda GK, Han W*. FoxO1 negatively regulates leptin-induced POMC transcription through its direct interaction with STAT3. Biochem J. 2015 Mar 1;466(2):291-8. doi: 10.1042/BJ20141109. PMID: 25510553.

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29: Yang W, Thein S, Lim CY, Ericksen RE, Sugii S, Xu F, Robinson RC, Kim JB,
Han W*. Arp2/3 complex regulates adipogenesis by controlling cortical actin
remodelling. Biochem J. 2014 Dec 1;464(2):179-92. doi: 10.1042/BJ20140805. PMID:
25220164.

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30: Liu T, Li H, Gounko NV, Zhou Z, Xu A, Hong W, Han W*. Detection of insulin
granule exocytosis by an electrophysiology method with high temporal resolution
reveals enlarged insulin granule pool in BIG3-knockout mice. Am J Physiol
Endocrinol Metab. 2014 Oct 1;307(7):E611-8. doi: 10.1152/ajpendo.00208.2014.
Epub 2014 Aug 19. PMID: 25139048.

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31: Li H, Wei S, Cheng K, Gounko NV, Ericksen RE, Xu A, Hong W, Han W*. BIG3
inhibits insulin granule biogenesis and insulin secretion. EMBO Rep. 2014
Jun;15(6):714-22. doi: 10.1002/embr.201338181. Epub 2014 Apr 7. PMID: 24711543;
PMCID: PMC4197882.

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32: Yang W, Thein S, Wang X, Bi X, Ericksen RE, Xu F, Han W*. BSCL2/seipin
regulates adipogenesis through actin cytoskeleton remodelling. Hum Mol Genet.
2014 Jan 15;23(2):502-13. doi: 10.1093/hmg/ddt444. Epub 2013 Sep 10. PMID:
24026679.

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33: Wei S, Soh SL, Qiu W, Yang W, Seah CJ, Guo J, Ong WY, Pang ZP, Han W*. Seipin
regulates excitatory synaptic transmission in cortical neurons. J Neurochem.
2013 Feb;124(4):478-89. doi: 10.1111/jnc.12099. Epub 2012 Dec 27. PMID:
23173741.

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34: Lee P, Leong W, Tan T, Lim M, Han W, Radda GK. In vivo hyperpolarized
carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase
flux in an insulin-resistant mouse model. Hepatology. 2013 Feb;57(2):515-24.
doi: 10.1002/hep.26028. Epub 2013 Jan 10. PMID: 22911492.

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35: Gustavsson N, Wu B, Han W*. Calcium sensing in exocytosis. Adv Exp Med Biol.
2012;740:731-57. doi: 10.1007/978-94-007-2888-2_32. PMID: 22453967.

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36: Han W, Li C. Linking type 2 diabetes and Alzheimer's disease. Proc Natl
Acad Sci U S A. 2010 Apr 13;107(15):6557-8. doi: 10.1073/pnas.1002555107. Epub
2010 Apr 12. PMID: 20385830; PMCID: PMC2872466.

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37: Gustavsson N, Wei SH, Hoang DN, Lao Y, Zhang Q, Radda GK, Rorsman P, Südhof TC, Han W*. Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas. J Physiol. 2009 Mar 15;587(Pt 6):1169-78. doi:
10.1113/jphysiol.2008.168005. Epub 2009 Jan 26. PMID: 19171650; PMCID:
PMC2674989.

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38: Gustavsson N, Lao Y, Maximov A, Chuang JC, Kostromina E, Repa JJ, Li C,
Radda GK, Südhof TC, Han W*. Impaired insulin secretion and glucose intolerance
in synaptotagmin-7 null mutant mice. Proc Natl Acad Sci U S A. 2008 Mar
11;105(10):3992-7. doi: 10.1073/pnas.0711700105. Epub 2008 Feb 28. PMID:
18308938; PMCID: PMC2268794.

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